Best of cannabinoid science this week...
In people with inflammatory bowel disease (IBD), ulcerative colitis patients who use cannabis had less intestinal surgeries & malnutrition while people with IBD who used cannabis had shorter hospital stays & less steroid use, intestinal obstruction, anemia, complications & mortality
Impact of Cannabis Use in Patients With Inflammatory Bowel Disease: Insights From the National Readmission Database 2019-2020
In people with arthritis, a survey reported cannabis use decreased pain with improvements in stiffness, fatigue & swelling
Patient-Reported Outcomes of Pain, Stiffness, and Fatigue Reduction in Rheumatoid and Psoriatic Arthritis With Cannabinoid Use
In case reports of twins with intractable epilepsy, they each achieved seizure suppression through different CBD regimens
Case reports of identical twins with developmental and epileptic encephalopathy with STXBP1 gene mutations for whom different CBD supplementations were markedly effective
In breast reduction surgery, a retrospective review found no impact from cannabis use
Marijuana and Its Implications in Breast Reduction Surgery Outcomes and Quality of Life: A Matched Analysis
For fibromyalgia, a review of 19 studies “showed an important improvement in pain, quality of life, and sleep habits” with no serious adverse events
Effectiveness and safety of cannabis-based products for medical use in patients with fibromyalgia syndrome: A systematic review
For the spasticity of multiple sclerosis, a review of 31 studies found the most commonly used medication to be nabiximols (1:1 THC:CBD sprays)
Cannabinoids for spasticity in patients with multiple sclerosis: A systematic review and meta-analysis
For anxiety & CBD, a review of 11 clinical trials found “the data suggest that CBD may reduce anxiety with minimal adverse effects when compared to a placebo”
The Impact of Cannabidiol Treatment on Anxiety Disorders: A Systematic Review of Randomized Controlled Clinical Trials
For pain, a review of CBD’s clinical & preclinical evidence
Cannabidiol (CBD): A Systematic Review of Clinical and Preclinical Evidence in the Treatment of Pain
And a review of using cannabinoids for pain management
Exploring the Therapeutic Potential of Cannabinoid in Pain Management
And a review of 74 cannabinoid pain studies covering 12k+ people
Efficiency of cannabis and cannabidiol in managing chronic pain syndromes: A comprehensive narrative review
“Cannabinoids were most effective in treating chronic secondary headache and orofacial pain, chronic secondary musculoskeletal pain, chronic secondary visceral pain, and chronic neuropathic pain.”
For chemotherapy & intestinal inflammation, a review of 81 articles on using cannabis to alleviate the symptoms
Medicinal Cannabis in Reducing Physical and Psychological Problems Caused by Chemotherapy and Intestinal Inflammation; Advantages and Challenges (A Review)
For sleep apnea, a review of nine studies using cannabinoids
Cannabinoids for obstructive sleep apnea: A systematic review
For microbial lung diseases, a review of using cannabis
Cannabis effectiveness on immunologic potency of pulmonary contagion
In humans skin cells, cannabinoid topicals reduced inflammation, promoted skin regeneration & improved structural functions
Exploring the Biological Activity of Phytocannabinoids Formulations for Skin Health Care: A Special Focus on Molecular Pathways
In a female rat model of PTSD, CBD reversed impairments in fear extinction, reduced learned helplessness & suppressed neuroinflammation in the prefrontal cortex
Cannabidiol Modulates Neuroinflammatory Markers in a PTSD Model Conducted on Female Rats
In a mouse model of obesity, cannabis reversed the damage to the DNA & mitochondria (powerhouse of the cell)
Effects of THC-rich Cannabis sativa extract on Biochemical Parameters in Obesity
In a mouse model of Alzheimer's disease, the long term administration of PEA prevented cognitive impairment, preserved motivation & lowered neuroinflammation
Long-term administration of ultra-micronized PEA alters disease progression in the Tg2576 mice and reveals neuroprotective effects on behavior, brain morphology and biochemistry
For CBD & cold brew coffee, a thesis project on their synergistic antioxidant effects
Synergistic Interactions and Emulsion Preparation of Antioxidant Potential of Cannabidiol and Cold Brew Coffee
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