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Research Roundup: Oct 17, 2024



Best of cannabinoid science this week...


In dogs living with pain, 8 weeks of full-spectrum cannabis oil decreased pain & proinflammatory cytokine levels as well as improved daily activity & the ability to use stairs

Efficacy and tolerability of full spectrum hemp oil in dogs living with pain in common household settings


For neurological disorders, a review of the minor cannabinoids

Unveiling the Potential of Phytocannabinoids: Exploring Marijuana’s Lesser-Known Constituents for Neurological Disorders


For wound healing, on the power of cannabis via reactive oxygen species regulation

Harnessing Cannabis sativa Oil for Enhanced Skin Wound Healing: The Role of Reactive Oxygen Species Regulation


In cosmetic dermatology, a review of CBD's potential

The Potential Role of Cannabidiol in Cosmetic Dermatology: A Literature Review


For rheumatological diseases, a review of 28 articles

Cannabis therapy in rheumatological diseases: A systematic review


For neuropathic pain, a review of targeting the endocannabinoid system

The endocannabinoid system as a therapeutic target in neuropathic pain: a review


For sleep in rats, a meta-analysis & review of the role of CB1 receptors

Systematic review/meta-analysis on the role of CB1R regulation in sleep-wake cycle in rats


In a rat model of high blood pressure, chronic CBD treatment improved their heart function & significantly reduced blood pressure

Chronic cannabidiol treatment induces cardiovascular improvement in renovascular hypertensive rats


In a rat model of depression, full-spectrum CBD, but not CBD isolate, reduced depressive-like behaviors

Repeated Administration of a Full-Spectrum Cannabidiol Product, Not a Cannabidiol Isolate, Reverses the Lipopolysaccharide-Induced Depressive-Like Behavior and Hypolocomotion in a Rat Model of Low-Grade Subchronic Inflammation


In a rat model of depression, CBD protected against anxiety & depressive-like behaviors & improved alterations in the gene expression of neuroinflammation

Effects of Cannabidiol (CBD) on Doxorubicin-Induced Anxiety and Depression-like Behaviors and mRNA Expression of Inflammatory Markers in Rats


In a mouse model of neuropathic pain from chemotherapy, cannabis reduced pain

Preliminary in vivo data on the analgesic effect of an EU-GMP-certified Cannabis sativa L. strain in an animal model of chemotherapy-induced chronic neuropathic pain


In a rat model of tremors, a 1:1 THC:CBD spray lessened tremors

Nabiximols (NBX) suppresses tremor in a rat Harmaline model of essential tremor


In models of gastroesophageal reflux disease (GERD – acid in the esophagus), PEA strongly decreased the inflammatory response

Palmitoylethanolamide (PEA) for Prevention of Gastroesophageal Inflammation: Insights from In Vitro Models

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